Tenoxicam
4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide
Molecular Identity
Tenoxicam
4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide
PubChem CID: 54677971
Tenoxicam is a thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain and inflammation in osteoarthritis and rheumatoid arthritis. It is also indicated for short term treatment of acute musculoskeletal disorders including strains, sprains and other soft-tissue injuries. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antipyretic and an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. It is a member of pyridines, a monocarboxylic acid amide, a thienothiazine and a heteroaryl hydroxy compound.
2D Structure
Properties
C13H11N3O4S2
Molecular Formula
337.40
Molecular Weight
g/mol
337.0191
Exact Mass
Da
1.1
XLogP
Drug-like (Lipinski: < 5)
136
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
7
H-Bond Acceptors
599
Complexity
SMILES
Canonical SMILES
SMILES: CN1C(=C(C2=C(S1(=O)=O)C=CS2)O)C(=O)NC3=CC=CC=N3Isomeric SMILES
SMILES: CN1C(=C(C2=C(S1(=O)=O)C=CS2)O)C(=O)NC3=CC=CC=N3Synonyms(20)
tenoxicam59804-37-4MobiflexTilcotilTenoxicamumRo 12-0068Ro 12-0068/000DTXSID8045486Ro-12-0068NSC-758397CHEBI:32192Z1R9N0A3994-Hydroxy-2-methyl-N-2-pyridyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxideRo-120068000DTXCID6025486
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Tenoxicam
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