tolfenamic acid
2-(3-chloro-2-methylanilino)benzoic acid
Molecular Identity
tolfenamic acid
2-(3-chloro-2-methylanilino)benzoic acid
PubChem CID: 610479
Tolfenamic acid is an aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 3-chloro-2-methylphenyl group. Tolfenamic acid is used specifically for relieving the pain of migraine. It also shows anticancer activity. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor and an EC 2.7.1.33 (pantothenate kinase) inhibitor. It is an aminobenzoic acid, an organochlorine compound and a secondary amino compound. It is functionally related to an anthranilic acid.
2D Structure
Properties
C14H12ClNO2
Molecular Formula
261.70
Molecular Weight
g/mol
261.0557
Exact Mass
Da
5.2
XLogP
Above Lipinski threshold
49.3
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
3
H-Bond Acceptors
298
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
tolfenamic acid13710-19-5Clotam2-[(3-Chloro-2-methylphenyl)amino]benzoic Acid2-((3-Chloro-2-methylphenyl)amino)benzoic acidAcido tolfenamicoAcide tolfenamiqueN-(3-Chloro-2-methylphenyl)anthranilic acidAcidum tolfenamicumN-(3-Chloro-o-tolyl)anthranilic acidN-(2-Methyl-3-chlorophenyl)anthranilic acidN-(3-Chloro-o-tolyl)-anthranilic acidNSC-757873DTXSID1045409N-(3-chloro-o-tolyl)anthranilic
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to tolfenamic acid
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