Molecular Identity
Tiratricol
2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid
PubChem CID: 5803
Tiratricol is a monocarboxylic acid that is (4-hydroxy-3,5-diiodophenyl)acetic acid in which the phenolic hydroxy group has been replaced by a 4-hydroxy-3-iodophenoxy group. It is a thyroid hormone analogue that has been used in the treatment of thyroid hormone resistance syndrome. It has a role as an antiviral agent, a nutraceutical, a thyroid hormone, an anti-obesity agent, an EC 1.3.5.2 [dihydroorotate dehydrogenase (quinone)] inhibitor and a human metabolite. It is a monocarboxylic acid, a member of phenols, an aromatic ether and an organoiodine compound.
2D Structure
Properties
C14H9I3O4
Molecular Formula
621.93
Molecular Weight
g/mol
621.7635
Exact Mass
Da
4.5
XLogP
Drug-like (Lipinski: < 5)
66.8
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
4
H-Bond Acceptors
356
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Tiratricol51-24-13,3',5-TRIIODOTHYROACETIC ACIDTriacTriiodothyroacetic acidTiratricolumTiracana2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acidT3-acetic acid2-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)acetic acidDTXSID20452323',3,5-Triiodothyroacetic acid3,5,3'-triiodothyroacetate4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodobenzeneacetic acidNSC-759294
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Tiratricol
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