latanoprost
propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate
Molecular Identity
latanoprost
propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate
PubChem CID: 5311221
Latanoprost is a prostaglandin Falpha that is the isopropyl ester prodrug of latanoprost free acid. Used in the treatment of open-angle glaucoma and ocular hypertension. It has a role as an EC 4.2.1.1 (carbonic anhydrase) inhibitor, an antihypertensive agent, an antiglaucoma drug and a prodrug. It is a triol, an isopropyl ester and a prostaglandins Falpha. It is functionally related to a latanoprost free acid.
2D Structure
Properties
C26H40O5
Molecular Formula
432.60
Molecular Weight
g/mol
432.2876
Exact Mass
Da
4.3
XLogP
Drug-like (Lipinski: < 5)
87
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
5
H-Bond Acceptors
526
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
latanoprost130209-82-4XalatanPhXA41PHXA-41XA41PhXA 41XA-41IYUZEHlatanoprost (isopropyl ester)latanoprostumpropan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate6Z5B6HVF6OXELPROSDTXSID1041057
Data from PubChem (NCBI)
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Trials and conditions connected to latanoprost
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