Sepantronium Bromide
1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione bromide
Molecular Identity
Sepantronium Bromide
1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione bromide
PubChem CID: 11178236
Sepantronium bromide is an organic bromide salt consisting of sepantronium cations and bromide anions. It has been found to selectively inhibit survivin (BIRC5) gene promoter activity and to down-regulate survivin in vitro, so leading to induction of apoptosis. It has a role as a survivin suppressant, an antineoplastic agent and an apoptosis inducer. It contains a sepantronium.
2D Structure
Properties
C20H19BrN4O3
Molecular Formula
443.30
Molecular Weight
g/mol
442.0641
Exact Mass
Da
78
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
6
H-Bond Acceptors
571
Complexity
SMILES
Canonical SMILES
SMILES: CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-]Isomeric SMILES
SMILES: CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-]Synonyms(20)
781661-94-7Sepantronium bromideYM155YM-155Ym 155bromuro de sepantroniobromure de sepantroniumsepantronii bromidum7H5Q4J1CM5CHEBI:139608DTXSID902288171H-Naphth(2,3-d)imidazolium, 4,9-dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazinylmethyl)-, bromideRefChem:931621Survivin Inhibitor YM155DTXCID40151308
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Sepantronium Bromide
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