Molecular Identity
Yohimbine
methyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
PubChem CID: 8969
Yohimbine is an indole alkaloid with alpha2-adrenoceptor antagonist activity. It is produced by Corynanthe johimbe and Rauwolfia serpentina. It has a role as a dopamine receptor D2 antagonist, an alpha-adrenergic antagonist and a serotonergic antagonist. It is functionally related to a yohimbic acid.
2D Structure
Properties
C21H26N2O3
Molecular Formula
354.40
Molecular Weight
g/mol
354.1943
Exact Mass
Da
2.9
XLogP
Drug-like (Lipinski: < 5)
65.6
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
4
H-Bond Acceptors
555
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Yohimbine146-48-5YohimbinQuebrachineCorynineQuebrachinAPHRODINEYohimbic acid methyl ester(+)-YohimbineYohimbinumYohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16alpha,17alpha)-17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester2Y49VWD90QDTXSID9040130methyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Yohimbine
Loading drug network...