Bizrolertinib
5-[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]oxy-6-methoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine
Molecular Identity
Bizrolertinib
5-[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]oxy-6-methoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-amine
PubChem CID: 146448634
2D Structure
Properties
C27H26F2N8O3
Molecular Formula
548.50
Molecular Weight
g/mol
548.2096
Exact Mass
Da
4.7
XLogP
Drug-like (Lipinski: < 5)
112
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
12
H-Bond Acceptors
848
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
BizrolertinibPerzebertinibZN-A-10412414056-31-65-[(4R)-3,3-difluoro-1-methylpiperidin-4-yl]oxy-6-methoxy-N-[3-methyl-4-([1,2,4]triazolo[1,5-c]pyrimidin-7-yloxy)phenyl]quinazolin-4-aminebizrolertinib [INN]Perzebertinib [WHO-DD]perzebertinib (deprecated INN)orb2565014UN8TM5120CSCHEMBL21807999GTPL13741PTKRHBXNNDLRPO-OAQYLSRUSA-NBDBM612264BDBM612287
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Bizrolertinib
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