MK-0536
6-[(3-chloro-4-fluorophenyl)methyl]-4-hydroxy-N,N-dimethyl-3,5-dioxo-2-propan-2-yl-7,8-dihydro-2,6-naphthyridine-1-carboxamide
Molecular Identity
MK-0536
6-[(3-chloro-4-fluorophenyl)methyl]-4-hydroxy-N,N-dimethyl-3,5-dioxo-2-propan-2-yl-7,8-dihydro-2,6-naphthyridine-1-carboxamide
PubChem CID: 54680316
2D Structure
Properties
C21H23ClFN3O4
Molecular Formula
435.90
Molecular Weight
g/mol
435.1361
Exact Mass
Da
2.3
XLogP
Drug-like (Lipinski: < 5)
81.2
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
5
H-Bond Acceptors
823
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(16)
MK-0536865298-83-56-(3-Chloro-4-Fluorobenzyl)-4-Hydroxy-N,N-Dimethyl-2-(1-Methylethyl)-3,5-Dioxo-2,3,5,6,7,8-Hexahydro-2,6-Naphthyridine-1-CarboxamideSCHEMBL2113536CHEMBL1237000HFCJYZIWLQSWGP-UHFFFAOYSA-NGLXC-22328EX-A6306Q274681102,6-Naphthyridine-1-carboxamide, 6-[(3-chloro-4-fluorophenyl)methyl]-2,3,5,6,7,8-hexahydro-4-hydroxy-N,N-dimethyl-2-(1-methylethyl)-3,5-dioxo-6-(3-chloro-4-fluorobenzyl)-4-hydroxy-2-isopropyl-n,n-dimethyl-3,5-dioxo-2,3,5,6,7,8-hexahydro-2,6-naphthyridine-1-carboxamide6-(3-chloro-4-fluorobenzyl)-4-hydroxy-N,N-dimethyl-2-isopropyl-3,5-dioxo-2,3,5,6,7,8-hexahydro-2,6-naphthyridine-1-carboxamide6-(3-chloro-4-fluorobenzyl)-4-hydroxy-N,N-dimethyl-3,5-dioxo-2-(propan-2-yl)-2,3,5,6,7,8-hexahydro-2,6-naphthyridine-1-carboxamide6-[(3-chloro-4-fluoro-phenyl)methyl]-4-hydroxy-2-isopropyl-N,N-dimethyl-3,5-dioxo-7,8-dihydro-2,6-naphthyridine-1-carboxamide6-[(3-chloro-4-fluorophenyl)methyl]-4-hydroxy-N,N,2-trimethyl-3,5-dioxo-7,8-dihydro-2,6-naphthyridine-1-carboxamide
Data from PubChem (NCBI)
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