Rly-2608
N-[(3R)-3-(2-chloro-5-fluorophenyl)-6-(5-cyano-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-1-oxo-2,3-dihydroisoindol-4-yl]-3-fluoro-5-(trifluoromethyl)benzamide
Molecular Identity
Rly-2608
N-[(3R)-3-(2-chloro-5-fluorophenyl)-6-(5-cyano-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-1-oxo-2,3-dihydroisoindol-4-yl]-3-fluoro-5-(trifluoromethyl)benzamide
PubChem CID: 166822065
2D Structure
Properties
C29H14ClF5N6O2
Molecular Formula
608.90
Molecular Weight
g/mol
608.0787
Exact Mass
Da
5.5
XLogP
Above Lipinski threshold
112
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
10
H-Bond Acceptors
1120
Complexity
SMILES
Canonical SMILES
SMILES: C1=CC(=C(C=C1F)C2C3=C(C=C(C=C3NC(=O)C4=CC(=CC(=C4)F)C(F)(F)F)C5=C(N6C(=NC=N6)C=C5)C#N)C(=O)N2)ClIsomeric SMILES
SMILES: C1=CC(=C(C=C1F)[C@H]2C3=C(C=C(C=C3NC(=O)C4=CC(=CC(=C4)F)C(F)(F)F)C5=C(N6C(=NC=N6)C=C5)C#N)C(=O)N2)ClSynonyms(20)
RLY-2608RLY 2608N-[(3R)-3-(2-chloro-5-fluorophenyl)-6-(5-cyano-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-1-oxo-2,3-dihydroisoindol-4-yl]-3-fluoro-5-(trifluoromethyl)benzamideN-((3R)-3-(2-chloro-5-fluorophenyl)-6-(5-cyano-(1,2,4)triazolo(1,5-a)pyridin-6-yl)-1-oxo-2,3-dihydroisoindol-4-yl)-3-fluoro-5-(trifluoromethyl)benzamideRefChem:179562PI3Ka Inhibitor RLY-2608Pan-mutant PI3Ka Inhibitor RLY-2608Mutant-selective PI3Ka Inhibitor RLY-2608Pan-mutant PIK3CA-selective Inhibitor RLY-2608Pan-mutant-selective PI3K-alpha Inhibitor RLY-26082733573-94-7ZovegalisibRLY2608(R)-N-(3-(2-Chloro-5-fluorophenyl)-6-(5-cyano-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-1-oxoisoindolin-4-yl)-3-fluoro-5-(trifluoromethyl)benzamide(R)-N-[3-(2-Chloro-5-fluorophenyl)-6-(5-cyano-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-1-oxoisoindolin-4-yl]-3-fluoro-5-(trifluoromethyl)benzamide
Data from PubChem (NCBI)
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