Alpha-Ketoglutarate
2-oxopentanedioate
Molecular Identity
Alpha-Ketoglutarate
2-oxopentanedioate
PubChem CID: 164533
2-oxoglutarate(2-) is an oxo dicarboxylate obtained by deprotonation of both carboxy groups of 2-oxoglutaric acid. It has a role as a geroprotector, a Saccharomyces cerevisiae metabolite, a human metabolite and an algal metabolite. It is functionally related to a glutarate(2-). It is a conjugate base of a 2-oxoglutarate(1-).
2D Structure
Properties
C5H4O5-2
Molecular Formula
144.08
Molecular Weight
g/mol
144.0059
Exact Mass
Da
0.4
XLogP
Drug-like (Lipinski: < 5)
97.3
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
5
H-Bond Acceptors
160
Complexity
SMILES
Canonical SMILES
SMILES: C(CC(=O)[O-])C(=O)C(=O)[O-]Isomeric SMILES
SMILES: C(CC(=O)[O-])C(=O)C(=O)[O-]Synonyms(20)
alpha-ketoglutarate2-oxopentanedioate2 Ketoglutarate2 Oxoglutaratealpha oxoglutarateRefChem:915532ketoglutarate64-15-32-oxoglutarate(2-)2-ketoglutaratePentanedioic acid, 2-oxo-, ion(2-)2-oxopentanedionate2-OxoglutamatePentanedioic acid,2-oxo-, ion(2-)alphaketoglutarate
Data from PubChem (NCBI)
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Trials and conditions connected to Alpha-Ketoglutarate
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