Molecular Identity
Bambuterol
[3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate
PubChem CID: 54766
Bambuterol is a carbamate ester that is terbutaline in which both of the phenolic hydroxy groups have been protected as the corresponding N,N-dimethylcarbamates. A long acting beta-adrenoceptor agonist used in the treatment of asthma, it is a prodrug for terbutaline. It has a role as a beta-adrenergic agonist, a bronchodilator agent, a sympathomimetic agent, an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an anti-asthmatic drug, a prodrug and a tocolytic agent. It is a carbamate ester and a member of phenylethanolamines. It is functionally related to a terbutaline.
2D Structure
Properties
C18H29N3O5
Molecular Formula
367.40
Molecular Weight
g/mol
367.2107
Exact Mass
Da
1.2
XLogP
Drug-like (Lipinski: < 5)
91.3
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
6
H-Bond Acceptors
446
Complexity
SMILES
Canonical SMILES
SMILES: CC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)OIsomeric SMILES
SMILES: CC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)OSynonyms(20)
Bambuterol81732-65-2Bambuterolum[3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamateY1850G1OVCCHEBI:553827(+-)-5-(2-(tert-Butylamino)-1-hydroxyethyl)-m-phenylene bis(dimethylcarbamate)DTXSID5048550(3-(2-(tert-butylamino)-1-hydroxyethyl)-5-(dimethylcarbamoyloxy)phenyl) N,N-dimethylcarbamateRefChem:1164115-(2-(tert-butylamino)-1-hydroxyethyl)-3-phenylene bis(dimethylcarbamate)DTXCID1028106R03CC123-(2-(tert-butylamino)-1-hydroxyethyl)-5-((dimethylcarbamoyl)oxy)phenyl N,N-dimethylcarbamateBambuterol (INN)
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Bambuterol
Loading drug network...