Belinostat
(E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide
Molecular Identity
Belinostat
(E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide
PubChem CID: 6918638
Belinostat is a hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. It has a role as an antineoplastic agent and an EC 3.5.1.98 (histone deacetylase) inhibitor. It is a hydroxamic acid, a sulfonamide and an olefinic compound.
2D Structure
Properties
C15H14N2O4S
Molecular Formula
318.30
Molecular Weight
g/mol
318.0674
Exact Mass
Da
1.7
XLogP
Drug-like (Lipinski: < 5)
104
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
5
H-Bond Acceptors
492
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Belinostat866323-14-0PXD101BeleodaqPXD-101PXD 101(2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamideNSC726630PX-105684NSC-726630F4H96P17NZ2-Propenamide, N-hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-, (2E)-(E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamideCHEBI:61076DTXSID60194378
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Belinostat
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