Bempedoic Acid
8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid
Molecular Identity
Bempedoic Acid
8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid
PubChem CID: 10472693
Bempedoic acid is an alpha,-dicarboxylic acid that is pentadecanedioic acid which is substituted by methyl groups groups at positions 2 and 14, and by a hydroxy group at position 8. It is a drug used for the treatment of high LDL cholesterol, which is sometimes referred to as 'bad cholesterol'. It has a role as an EC 2.3.3.8 (ATP citrate synthase) inhibitor, an antilipemic drug and a prodrug.
2D Structure
Properties
C19H36O5
Molecular Formula
344.50
Molecular Weight
g/mol
344.2563
Exact Mass
Da
4.8
XLogP
Drug-like (Lipinski: < 5)
94.8
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
5
H-Bond Acceptors
351
Complexity
SMILES
Canonical SMILES
SMILES: CC(C)(CCCCCC(CCCCCC(C)(C)C(=O)O)O)C(=O)OIsomeric SMILES
SMILES: CC(C)(CCCCCC(CCCCCC(C)(C)C(=O)O)O)C(=O)OSynonyms(20)
bempedoic acid738606-46-7ETC-10028-Hydroxy-2,2,14,14-tetramethylpentadecanedioic acidNexletolESP-55016acido bempedoicoETC1002acide bempedoiqueacidum bempedoicumETC 1002ESP 550161EJ6Z6Q368Pentadecanedioic acid, 8-hydroxy-2,2,14,14-tetramethyl-CHEBI:149601
Data from PubChem (NCBI)
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Trials and conditions connected to Bempedoic Acid
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