Molecular Identity
BETAMETHASONE DIPROPIONATE
[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
PubChem CID: 21800
Betamethasone dipropionate is a steroid ester that is betamethasone in which the hydroxy hydrogens at positions 17 and 21 are replaced by propanoyl groups. It is used in combination with calcipotriene hydrate, a synthetic vitamin D analogue, for the topical treatment of plaque psoriasis in adult patients. It has a role as an antipsoriatic. It is an 11beta-hydroxy steroid, a propanoate ester, a 20-oxo steroid, a steroid ester, a fluorinated steroid and a 3-oxo-Delta(1),Delta(4)-steroid. It is functionally related to a betamethasone.
2D Structure
Properties
C28H37FO7
Molecular Formula
504.60
Molecular Weight
g/mol
504.2523
Exact Mass
Da
3.6
XLogP
Drug-like (Lipinski: < 5)
107
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
8
H-Bond Acceptors
1050
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
BETAMETHASONE DIPROPIONATEDiprosoneDiprolene5593-20-4AlphatrexMaxivateBetamethasone 17,21-dipropionateDiprolene AFRinderon DPDiprospanSch 11460SernivoSch-11460beta-Methasone 17,21-dipropionateBetamethasone (as dipropionate)
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to BETAMETHASONE DIPROPIONATE
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