Cisatracurium besylate
benzenesulfonate;5-[3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate
Molecular Identity
Cisatracurium besylate
benzenesulfonate;5-[3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate
PubChem CID: 62886
Cisatracurium besylate is the (1R,1'R,2R,2'R)-diastereoisomer of atracurium besylate. Commercial preparations of atracurium are mixtures of 10 stereoisomers, of which cisatracurium generally constitutes about 15%. Cisatracurium besylate is about 3 times more potent than the mixture of atracurium isomers as a neuromuscular blocking agent, and is used as a muscle relaxant for endotracheal intubation, to aid controlled ventilation, and in general anaesthesia. It has a role as a nicotinic antagonist and a muscle relaxant. It is an atracurium besylate, a quaternary ammonium salt and an organosulfonate salt. It contains a cisatracurium.
2D Structure
Properties
C65H82N2O18S2
Molecular Formula
1243.50
Molecular Weight
g/mol
1242.5004
Exact Mass
Da
258
TPSA
May have limited oral absorption
0
H-Bond Donors
18
H-Bond Acceptors
1560
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Cisatracurium besylate96946-42-8NimbexCisatracurium besilateNIMBEX PRESERVATIVE FREE51W89Cisatracurium (as besilate)80YS8O1MBSBesilato de cisatracurioBesilate de cisatracuriumCisatracurium Besylate Preservative FreeCHEBI:3721(1R,2R)-2-(2-Carboxyethyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinolinium benzenesulfonate, pentamethylene esterDTXSID1089504551-W89
Data from PubChem (NCBI)
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