Molecular Identity
Desipramine
3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
PubChem CID: 2995
Desipramine is a dibenzoazepine consisting of 10,11-dihydro-5H-dibenzo[b,f]azepine substituted on nitrogen with a 3-(methylamino)propyl group. It has a role as an antidepressant, an adrenergic uptake inhibitor, an alpha-adrenergic antagonist, a H1-receptor antagonist, a cholinergic antagonist, a serotonin uptake inhibitor, an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor, an EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor and a drug allergen. It is a dibenzoazepine and a secondary amino compound.
2D Structure
Properties
C18H22N2
Molecular Formula
266.40
Molecular Weight
g/mol
266.1783
Exact Mass
Da
4.9
XLogP
Drug-like (Lipinski: < 5)
15.3
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
2
H-Bond Acceptors
267
Complexity
SMILES
Canonical SMILES
SMILES: CNCCCN1C2=CC=CC=C2CCC3=CC=CC=C31Isomeric SMILES
SMILES: CNCCCN1C2=CC=CC=C2CCC3=CC=CC=C31Synonyms(20)
desipramineNorimipramine50-47-5DesmethylimipramineMonodemethylimipramineDesipraminDemethylimipramineDesimipramineDimethylimipramineDezipramineDesipraminaMethylaminopropyliminodibenzylImipramine, demethyl-desipraminumDesimpramine
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Desipramine
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