Molecular Identity
galanthamine
(1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol
PubChem CID: 9651
Galanthamine is a benzazepine alkaloid isolated from certain species of daffodils. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor, a cholinergic drug, an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an antidote to curare poisoning and a plant metabolite. It is an organic heterotetracyclic compound, a benzazepine alkaloid, a benzazepine alkaloid fundamental parent and a tertiary amino compound. It is a conjugate base of a galanthamine(1+).
2D Structure
Properties
C17H21NO3
Molecular Formula
287.35
Molecular Weight
g/mol
287.1521
Exact Mass
Da
1.8
XLogP
Drug-like (Lipinski: < 5)
41.9
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
4
H-Bond Acceptors
440
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
galanthamineGalantamine357-70-0(-)-GalanthamineLycoremineGalantaminaReminyl(-)-GalantamineGalanthaminumGalantaminumNSC-1000580D3Q044KCA(1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-olDTXSID2045606CHEBI:42944
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to galanthamine
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