Golidocitinib
(2R)-N-[3-[2-[(3-methoxy-1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-1H-indol-7-yl]-2-(4-methylpiperazin-1-yl)propanamide
Molecular Identity
Golidocitinib
(2R)-N-[3-[2-[(3-methoxy-1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-1H-indol-7-yl]-2-(4-methylpiperazin-1-yl)propanamide
PubChem CID: 126715380
2D Structure
Properties
C25H31N9O2
Molecular Formula
489.60
Molecular Weight
g/mol
489.2601
Exact Mass
Da
1.9
XLogP
Drug-like (Lipinski: < 5)
116
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
8
H-Bond Acceptors
736
Complexity
SMILES
Canonical SMILES
SMILES: CC(C(=O)NC1=CC=CC2=C1NC=C2C3=NC(=NC=C3)NC4=CN(N=C4OC)C)N5CCN(CC5)CIsomeric SMILES
SMILES: C[C@H](C(=O)NC1=CC=CC2=C1NC=C2C3=NC(=NC=C3)NC4=CN(N=C4OC)C)N5CCN(CC5)CSynonyms(20)
golidocitinibAZD-4205AZD4205UNII-3BY9Z3M34G3BY9Z3M34G(2R)-N-[3-[2-[(3-methoxy-1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-1H-indol-7-yl]-2-(4-methylpiperazin-1-yl)propanamideGOLIDOCITINIB [INN](2R)-N-(3-(2-((3-methoxy-1-methylpyrazol-4-yl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-2-(4-methylpiperazin-1-yl)propanamide(ALPHAR)-N-(3-(2-((3-METHOXY-1-METHYL-1H-PYRAZOL-4-YL)AMINO)-4-PYRIMIDINYL)-1H-INDOL-7-YL)-ALPHA,4-DIMETHYL-1-PIPERAZINEACETAMIDE(alphaR)-N-[3-[2-[(3-Methoxy-1-methyl-1H-pyrazol-4-yl)amino]-4-pyrimidinyl]-1H-indol-7-yl]-alpha,4-dimethyl-1-piperazineacetamideAZD 4205RefChem:144119JAK1 Inhibitor AZD4205(.ALPHA.R)-N-(3-(2-((3-METHOXY-1-METHYL-1H-PYRAZOL-4-YL)AMINO)-4-PYRIMIDINYL)-1H-INDOL-7-YL)-.ALPHA.,4-DIMETHYL-1-PIPERAZINEACETAMIDE2091134-68-6
Data from PubChem (NCBI)
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Trials and conditions connected to Golidocitinib
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