Lapatinib
N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
Molecular Identity
Lapatinib
N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
PubChem CID: 208908
Lapatinib is a member of furans, an organochlorine compound, an organofluorine compound and a member of quinazolines. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It is functionally related to a monofluorobenzene.
2D Structure
Properties
C29H26ClFN4O4S
Molecular Formula
581.10
Molecular Weight
g/mol
580.1347
Exact Mass
Da
5.1
XLogP
Above Lipinski threshold
115
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
9
H-Bond Acceptors
898
Complexity
SMILES
Canonical SMILES
SMILES: CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)ClIsomeric SMILES
SMILES: CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)ClSynonyms(20)
Lapatinib231277-92-2GW572016GW 572016GSK 572016GW-572016DTXSID7046675n-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamineGSK572016GSK-5720160VUA21238FN-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amineGW-572016XDTXCID5026675CHEBI:49603
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Lapatinib
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