Lapatinib Ditosylate
N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine;bis(4-methylbenzenesulfonic acid);hydrate
Molecular Identity
Lapatinib Ditosylate
N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine;bis(4-methylbenzenesulfonic acid);hydrate
PubChem CID: 11557040
Lapatinib ditosylate monohydrate is a member of quinazolines.
2D Structure
Properties
C43H44ClFN4O11S3
Molecular Formula
943.50
Molecular Weight
g/mol
942.1841
Exact Mass
Da
241
TPSA
May have limited oral absorption
5
H-Bond Donors
16
H-Bond Acceptors
1100
Complexity
SMILES
Canonical SMILES
SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl.OIsomeric SMILES
SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl.OSynonyms(20)
Tyverblapatinib tosilateTycerbGW572016FLapatinib tosilate hydrateGW-572016FG873GX646RLapatinib ditoluenesulfonate monohydrate4-Quinazolinamine, N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl), bis(4-methylbenzenesulfonate), monohydrateN-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine bis(4-methylbenzenesulfonate) monohydrateN-[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]furan-2-yl]quinazolin-4-amine bis(4-methylbenzenesulfonate) monohydrateRefChem:55454Lapatinib Ditosylate388082-78-8Lapatinib ditosylate hydrate
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Lapatinib Ditosylate
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