Lenalidomide
3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
Molecular Identity
Lenalidomide
3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
PubChem CID: 216326
Lenalidomide is a dicarboximide that consists of 1-oxoisoindoline bearing an amino substituent at position 4 and a 2,6-dioxopiperidin-3-yl group at position 2. Inhibits the secretion of TNF-alpha. It has a role as an antineoplastic agent, an angiogenesis inhibitor and an immunomodulator. It is a member of isoindoles, an aromatic amine, a dicarboximide and a member of piperidones.
2D Structure
Properties
C13H13N3O3
Molecular Formula
259.26
Molecular Weight
g/mol
259.0957
Exact Mass
Da
-0.5
XLogP
Drug-like (Lipinski: < 5)
92.5
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
4
H-Bond Acceptors
437
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Lenalidomide191732-72-6RevlimidRevimid3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dioneCC-50132,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dioneCDC 501CDC-501LenalidomidaDTXSID8046664NSC-747972F0P408N6V41-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline
Data from PubChem (NCBI)
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Trials and conditions connected to Lenalidomide
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