Levoleucovorin
(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid
Molecular Identity
Levoleucovorin
(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid
PubChem CID: 135398559
(6S)-5-formyltetrahydrofolic acid is the pharmacologically active (6S)-stereoisomer of 5-formyltetrahydrofolic acid. It has a role as a metabolite and an antineoplastic agent. It is a conjugate acid of a (6S)-5-formyltetrahydrofolate(2-).
2D Structure
Properties
C20H23N7O7
Molecular Formula
473.40
Molecular Weight
g/mol
473.1659
Exact Mass
Da
-1.2
XLogP
Drug-like (Lipinski: < 5)
216
TPSA
May have limited oral absorption
7
H-Bond Donors
10
H-Bond Acceptors
911
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
LevoleucovorinLevofolinic acidL-Folinic acidLevofolene68538-85-2(S)-Leucovorin(6S)-Leucovorin(6S)-Folinic acid(6S)-5-Formyl-5,6,7,8-tetrahydrofolic acidKHAPZORYLFP-754990S25980YDTXSID4023204CHEBI:63606L-Glutamic acid, N-(4-((((6S)-2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-
Data from PubChem (NCBI)
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