linezolid
N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
Molecular Identity
linezolid
N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
PubChem CID: 441401
Linezolid is an organofluorine compound that consists of 1,3-oxazolidin-2-one bearing an N-3-fluoro-4-(morpholin-4-yl)phenyl group as well as an acetamidomethyl group at position 5. A synthetic antibacterial agent that inhibits bacterial protein synthesis by binding to a site on 23S ribosomal RNA of the 50S subunit and prevents further formation of a functional 70S initiation complex. It has a role as an antibacterial drug and a protein synthesis inhibitor. It is a member of acetamides, an organofluorine compound, a member of morpholines and an oxazolidinone.
2D Structure
Properties
C16H20FN3O4
Molecular Formula
337.35
Molecular Weight
g/mol
337.1438
Exact Mass
Da
0.7
XLogP
Drug-like (Lipinski: < 5)
71.1
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
6
H-Bond Acceptors
472
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
linezolid165800-03-3ZyvoxPNU-100766U-100766LINEZOLIDEISQ9I6J12JN-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamideN-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamideDTXSID5046489U-100,766PNU100766DTXCID3026489CHEBI:63607Acetamide, N-((3-(3-fluoro-4-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)-, (S)-
Data from PubChem (NCBI)
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