Lometrexol
(2S)-2-[[4-[2-[(6R)-2-amino-4-oxo-5,6,7,8-tetrahydro-3H-pyrido[2,3-d]pyrimidin-6-yl]ethyl]benzoyl]amino]pentanedioic acid
Molecular Identity
Lometrexol
(2S)-2-[[4-[2-[(6R)-2-amino-4-oxo-5,6,7,8-tetrahydro-3H-pyrido[2,3-d]pyrimidin-6-yl]ethyl]benzoyl]amino]pentanedioic acid
PubChem CID: 135413518
2D Structure
Properties
C21H25N5O6
Molecular Formula
443.50
Molecular Weight
g/mol
443.1805
Exact Mass
Da
0.3
XLogP
Drug-like (Lipinski: < 5)
183
TPSA
May have limited oral absorption
6
H-Bond Donors
8
H-Bond Acceptors
831
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Lometrexol106400-81-1Lometrexolum5,10-dideazatetrahydrofolic acid6P3AVY8A7QLY2646185,10-dideazatetrahydrofolateL-Glutamic acid, N-(4-(2-(2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-d)pyrimidin-6-yl)ethyl)benzoyl)-, (R)-L-Glutamic acid, N-(4-(2-((6R)-2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-d)pyrimidin-6-yl)ethyl)benzoyl)-5,10-Dideaza-5,6,7,8-tetrahydrofolic acidNSC6600255,10-DDTFRefChem:800022(6R)-DDATHF6R-5,10-Dideazatetrahydrofolate
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Lometrexol
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