Morphine
(4R,4aR,7S,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
Molecular Identity
Morphine
(4R,4aR,7S,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
PubChem CID: 5288826
Morphine is a morphinane alkaloid that is a highly potent opiate analgesic psychoactive drug. Morphine acts directly on the central nervous system (CNS) to relieve pain but has a high potential for addiction, with tolerance and both physical and psychological dependence developing rapidly. Morphine is the most abundant opiate found in Papaver somniferum (the opium poppy). It has a role as a geroprotector, an opioid analgesic, a vasodilator agent, a xenobiotic, an anaesthetic, a mu-opioid receptor agonist, a plant metabolite, an environmental contaminant and a drug allergen. It is a morphinane alkaloid, an organic heteropentacyclic compound and a tertiary amino compound. It is a conjugate base of a morphine(1+). It derives from a hydride of a morphinan.
2D Structure
Properties
C17H19NO3
Molecular Formula
285.34
Molecular Weight
g/mol
285.1365
Exact Mass
Da
0.8
XLogP
Drug-like (Lipinski: < 5)
52.9
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
4
H-Bond Acceptors
494
Complexity
SMILES
Canonical SMILES
SMILES: CN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)OIsomeric SMILES
SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)OSynonyms(20)
morphineMorphiaMorphiumMorphina(-)-MorphineMorphinumOspalivinaMorphinDuromorph57-27-2MeconiumMorphinismNepentheDulcontinRoxanol
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Morphine
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