Mosapride
4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide
Molecular Identity
Mosapride
4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide
PubChem CID: 119584
Mosapride is a racemate comprising equimolar amounts of (R)- and (S)-mosapride. It is a gastroprokinetic agent which acts on 5-hydroxytryptamine type 4 (5-HT4) receptors in the gastrointestinal plexus, consequently increasing the release of acetylcholine and hence enhancing gastrointestinal motility and gastric emptying. It has a role as a serotonergic agonist and a gastrointestinal drug. It contains a (R)-mosapride and a (S)-mosapride.
2D Structure
Properties
C21H25ClFN3O3
Molecular Formula
421.90
Molecular Weight
g/mol
421.1568
Exact Mass
Da
2.8
XLogP
Drug-like (Lipinski: < 5)
76.8
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
6
H-Bond Acceptors
521
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Mosapride112885-41-34-amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamideMosart4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamidemosapridaI8MFJ1C0BY4-amino-5-chloro-2-ethoxy-N-({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)benzamideDTXSID2048408CHEBI:94373CHEBI:167204mosapridum4-amino-5-chloro-2-ethoxy-N-((4-((4-fluorophenyl)methyl)morpholin-2-yl)methyl)benzamide4-amino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)-2-morpholinyl]methyl]benzamideRefChem:159818
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Mosapride
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