Naloxone Hydrochloride
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride
Molecular Identity
Naloxone Hydrochloride
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one;hydrochloride
PubChem CID: 5464092
Naloxone hydrochloride is a hydrochloride resulting from the formal reaction of equimolar amounts of naloxone and hydrogen chloride. A specific opioid antagonist, it is used to reverse the effects of opioids, both following their use of opioids during surgery and in cases of known or suspected opioid overdose. It has a role as a central nervous system depressant, a mu-opioid receptor antagonist and an antidote to opioid poisoning. It contains a naloxone(1+).
2D Structure
Properties
C19H22ClNO4
Molecular Formula
363.80
Molecular Weight
g/mol
363.1237
Exact Mass
Da
70
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
5
H-Bond Acceptors
594
Complexity
SMILES
Canonical SMILES
SMILES: C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.ClIsomeric SMILES
SMILES: C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O.ClSynonyms(20)
Naloxone hydrochlorideNaloxone HCl357-08-4EvzioNIH 7890REZENOPYRIVIVEEN-15304KLOXXADOAnhydrous naloxone hydrochlorideF850569PQRNSC-757109Naloxone hydrochloride anhydrousNaloxoni hydrochloridum anhydrousCHEBI:31892
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Naloxone Hydrochloride
Loading drug network...