Molecular Identity
Oxymetazoline
6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
PubChem CID: 4636
Oxymetazoline is a member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion. It has a role as a sympathomimetic agent, an alpha-adrenergic agonist, a vasoconstrictor agent and a nasal decongestant. It is a member of phenols, a carboxamidine and a member of imidazolines. It is a conjugate base of an oxymetazoline(1+).
2D Structure
Properties
C16H24N2O
Molecular Formula
260.37
Molecular Weight
g/mol
260.1889
Exact Mass
Da
2.9
XLogP
Drug-like (Lipinski: < 5)
44.6
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
2
H-Bond Acceptors
345
Complexity
SMILES
Canonical SMILES
SMILES: CC1=CC(=C(C(=C1CC2=NCCN2)C)O)C(C)(C)CIsomeric SMILES
SMILES: CC1=CC(=C(C(=C1CC2=NCCN2)C)O)C(C)(C)CSynonyms(20)
oxymetazoline1491-59-4OxymethazolineHazolOximetazolinumOxylazineRhinofrenolSinerolIliadinNavisinNezerilNafrineOxymetozolineOximetazolinaOxymetazolinum
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Oxymetazoline
Loading drug network...