Palonosetron Hydrochloride
(3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one;hydrochloride
Molecular Identity
Palonosetron Hydrochloride
(3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one;hydrochloride
PubChem CID: 6918303
Palonosetron hydrochloride is a hydrochloride obtained by combining palonosetron with one molar equivalent of hydrogen chloride; an antiemetic used in combination with netupitant (under the trade name Akynzeo) to treat nausea and vomiting in patients undergoing cancer chemotherapy. It has a role as a serotonergic antagonist and an antiemetic. It contains a palonosetron(1+).
2D Structure
Properties
C19H25ClN2O
Molecular Formula
332.90
Molecular Weight
g/mol
332.1655
Exact Mass
Da
23.6
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
2
H-Bond Acceptors
456
Complexity
SMILES
Canonical SMILES
SMILES: C1CC2CN(C(=O)C3=CC=CC(=C23)C1)C4CN5CCC4CC5.ClIsomeric SMILES
SMILES: C1C[C@@H]2CN(C(=O)C3=CC=CC(=C23)C1)[C@@H]4CN5CCC4CC5.ClSynonyms(20)
Palonosetron hydrochloride135729-62-3PALONOSETRON HClDTXSID8046610RS-25259-197Palonocetron hydrochloridePalonosetron (as hydrochloride)RS 25259-19723310D4I19DTXCID6026610CHEBI:85157AKYNZEO COMPONENT PALONOSETRON HYDROCHLORIDEposfreaPalonsetron hydrochlorideRefChem:56727
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Palonosetron Hydrochloride
Loading drug network...