Pamiparib
(2R)-14-fluoro-2-methyl-6,9,10,19-tetrazapentacyclo[14.2.1.02,6.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one
Molecular Identity
Pamiparib
(2R)-14-fluoro-2-methyl-6,9,10,19-tetrazapentacyclo[14.2.1.02,6.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one
PubChem CID: 135565554
2D Structure
Properties
C16H15FN4O
Molecular Formula
298.31
Molecular Weight
g/mol
298.1230
Exact Mass
Da
1.6
XLogP
Drug-like (Lipinski: < 5)
60.5
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
4
H-Bond Acceptors
566
Complexity
SMILES
Canonical SMILES
SMILES: CC12CCCN1CC3=NNC(=O)C4=C5C3=C2NC5=CC(=C4)FIsomeric SMILES
SMILES: C[C@]12CCCN1CC3=NNC(=O)C4=C5C3=C2NC5=CC(=C4)FSynonyms(20)
Pamiparib1446261-44-48375F9S90C5,6,7a,11-Tetraazacyclohepta(def)cyclopenta(a)fluoren-4(7H)-one, 2-fluoro-5,8,9,10,10a,11-hexahydro-10a-methyl-, (10aR)-5,6,7a,11-Tetraazacyclohepta[def]cyclopenta[a]fluoren-4(7H)-one, 2-fluoro-5,8,9,10,10a,11-hexahydro-10a-methyl-, (10aR)-pamiparibumRefChem:858446PARP Inhibitor BGB-290(2R)-14-fluoro-2-methyl-6,9,10,19-tetraazapentacyclo(14.2.1.0^(2,6).0^(8,18).0^(12,17))nonadeca-1(18),8,12(17),13,15-pentaen-11-oneBGB-290Pamiparib [INN]Pamiparib [USAN]BGB290(2R)-14-fluoro-2-methyl-6,9,10,19-tetrazapentacyclo[14.2.1.02,6.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one(R)-2-fluoro-10a-methyl-7,8,9,10,10a,11-hexahydro-5,6,7a,11-tetraazacyclohepta[def]cyclopenta[a]fluoren-4(5H)-one
Data from PubChem (NCBI)
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