Pazopanib Hydrochloride
5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydrochloride
Molecular Identity
Pazopanib Hydrochloride
5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydrochloride
PubChem CID: 11525740
Pazopanib hydrochloride is a hydrochloride salt prepared from equimolar amounts of pazopanib and hydrochloric acid. Used for treatment of kidney cancer. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor, an angiogenesis modulating agent and a vascular endothelial growth factor receptor antagonist. It contains a pazopanib(1+).
2D Structure
Properties
C21H24ClN7O2S
Molecular Formula
474.00
Molecular Weight
g/mol
473.1401
Exact Mass
Da
127
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
8
H-Bond Acceptors
717
Complexity
SMILES
Canonical SMILES
SMILES: CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.ClIsomeric SMILES
SMILES: CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N.ClSynonyms(20)
Pazopanib hydrochloride635702-64-6pazopanib HClUNII-33Y9ANM545pazopanib monohydrochloridePazopanib (as hydrochloride)33Y9ANM5455-((4-((2,3-DIMETHYL-2H-INDAZOL-6-YL)(METHYL)AMINO)PYRIMIDIN-2-YL)AMINO)-2-METHYLBENZENESULFONAMIDE HYDROCHLORIDECHEBI:71217DTXSID70212956NSC7377545-((4-((2,3-Dimethyl-2H-indazol-6-yl)methylamino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide monohydrochloride5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide hydrochlorideBenzenesulfonamide, 5-((4-((2,3-dimethyl-2H-indazol-6-yl)methylamino)-2-pyrimidinyl)amino)-2-methyl-, monohydrochloridePAZOPANIB HYDROCHLORIDE (MART.)
Data from PubChem (NCBI)
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Trials and conditions connected to Pazopanib Hydrochloride
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