Perifosine
(1,1-dimethylpiperidin-1-ium-4-yl) octadecyl phosphate
Molecular Identity
Perifosine
(1,1-dimethylpiperidin-1-ium-4-yl) octadecyl phosphate
PubChem CID: 148177
Perifosine is a phospholipid consisting of 1,1-dimethylpiperidinium-4-yl hydrogen phosphate in which the hydrogen is replaced by a stearyl (octadecyl) group. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It is a phospholipid and an ammonium betaine. It is functionally related to an octadecan-1-ol.
2D Structure
Properties
C25H52NO4P
Molecular Formula
461.70
Molecular Weight
g/mol
461.3634
Exact Mass
Da
8.3
XLogP
Above Lipinski threshold
58.6
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
4
H-Bond Acceptors
454
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Perifosine157716-52-4KRX-0401(1,1-dimethylpiperidin-1-ium-4-yl) octadecyl phosphateD 21266NSC 639966perifosinaNSC-6399661,1-dimethylpiperidinium-4-yl octadecyl phosphateD-21266AEZS-104DTXSID3048946octadecyl-(1,1-dimethyl-4-piperidylio)phosphate2GWV496552DTXCID0028872
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Perifosine
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