Molecular Identity
perphenazine
2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol
PubChem CID: 4748
Perphenazine is a phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10. It has a role as a phenothiazine antipsychotic drug, a dopaminergic antagonist and an antiemetic. It is an organochlorine compound, a member of phenothiazines, a N-alkylpiperazine and a N-(2-hydroxyethyl)piperazine. It derives from a hydride of a 10H-phenothiazine.
2D Structure
Properties
C21H26ClN3OS
Molecular Formula
404.00
Molecular Weight
g/mol
403.1485
Exact Mass
Da
4.2
XLogP
Drug-like (Lipinski: < 5)
55.3
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
5
H-Bond Acceptors
463
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
perphenazine58-39-9TrilafonPerphenazinPerfenazineEtaperazineChlorpiprazineEtaperazinEthaperazineFentazinDecentanPerphenanPerfenazinaThilatazinTrifaron
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to perphenazine
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