Molecular Identity
Pirfenidone
5-methyl-1-phenylpyridin-2-one
PubChem CID: 40632
Pirfenidone is a pyridone that is 2-pyridone substituted at positions 1 and 5 by phenyl and methyl groups respectively. An anti-inflammatory drug used for the treatment of idiopathic pulmonary fibrosis. It has a role as an antifibrotic agent, a non-steroidal anti-inflammatory drug, a non-narcotic analgesic and an antipyretic.
2D Structure
Properties
C12H11NO
Molecular Formula
185.22
Molecular Weight
g/mol
185.0841
Exact Mass
Da
1.9
XLogP
Drug-like (Lipinski: < 5)
20.3
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
1
H-Bond Acceptors
285
Complexity
SMILES
Canonical SMILES
SMILES: CC1=CN(C(=O)C=C1)C2=CC=CC=C2Isomeric SMILES
SMILES: CC1=CN(C(=O)C=C1)C2=CC=CC=C2Synonyms(20)
PIRFENIDONE53179-13-8EsbrietPirespaAMR-69PirfenidonaPirfenidonum5-methyl-1-phenylpyridin-2-one2(1H)-Pyridinone, 5-methyl-1-phenyl-5-Methyl-1-phenyl-2(1H)-pyridoneAMR 69DTXSID4045183D7NLD2JX7UNSC-748456DTXCID2025183
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Pirfenidone
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