Molecular Identity
Promethazine
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine
PubChem CID: 4927
Promethazine is a tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety. It has a role as an anticoronaviral agent, a sedative, a local anaesthetic, a H1-receptor antagonist, an anti-allergic agent, an antiemetic and an antipruritic drug. It is a tertiary amine and a member of phenothiazines. It is a conjugate base of a promethazine(1+).
2D Structure
Properties
C17H20N2S
Molecular Formula
284.40
Molecular Weight
g/mol
284.1347
Exact Mass
Da
4.8
XLogP
Drug-like (Lipinski: < 5)
31.8
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
3
H-Bond Acceptors
298
Complexity
SMILES
Canonical SMILES
SMILES: CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)CIsomeric SMILES
SMILES: CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)CSynonyms(20)
promethazine60-87-7ProazamineDipherganProtazineVallergineDimappPromethazinFarganProcitPromazinamidePromezathinePrometazinProthazinHiberna
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Promethazine
Loading drug network...