Molecular Identity
pyrazinamide
pyrazine-2-carboxamide
PubChem CID: 1046
Pyrazinecarboxamide is a monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis. It has a role as an antitubercular agent and a prodrug. It is a monocarboxylic acid amide, a member of pyrazines and a N-acylammonia.
2D Structure
Properties
C5H5N3O
Molecular Formula
123.11
Molecular Weight
g/mol
123.0433
Exact Mass
Da
-0.6
XLogP
Drug-like (Lipinski: < 5)
68.9
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
3
H-Bond Acceptors
115
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
pyrazinamidepyrazinecarboxamide98-96-4pyrazine-2-carboxamideZinamideAldinamideTebrazidpyrazinoic acid amideAldinamidFarmizinaPirazimidaPirazinamidUnipyranamideEprazinNovamid
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to pyrazinamide
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