Molecular Identity
Tazarotene
ethyl 6-[2-(4,4-dimethyl-2,3-dihydrothiochromen-6-yl)ethynyl]pyridine-3-carboxylate
PubChem CID: 5381
Tazarotene is the ethyl ester of tazarotenic acid. A prodrug for tazarotenic acid, it is used for the treatment of psoriasis, acne, and sun-damaged skin. It has a role as a keratolytic drug, a prodrug and a teratogenic agent. It is an ethyl ester, a member of pyridines, a retinoid, a thiochromane and an acetylenic compound. It is functionally related to a tazarotenic acid.
2D Structure
Properties
C21H21NO2S
Molecular Formula
351.50
Molecular Weight
g/mol
351.1293
Exact Mass
Da
4.9
XLogP
Drug-like (Lipinski: < 5)
64.5
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
4
H-Bond Acceptors
547
Complexity
SMILES
Canonical SMILES
SMILES: CCOC(=O)C1=CN=C(C=C1)C#CC2=CC3=C(C=C2)SCCC3(C)CIsomeric SMILES
SMILES: CCOC(=O)C1=CN=C(C=C1)C#CC2=CC3=C(C=C2)SCCC3(C)CSynonyms(20)
tazarotene118292-40-3TazoracEthyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinateZoracAvageAGN-190168FabiortazarotenotazarotenumDTXSID5046691Idp-12381BDR9Y8PSAGN190168ARAZLO
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Tazarotene
Loading drug network...