Tenofovir Disoproxil Fumarate
[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate;(E)-but-2-enedioic acid
Molecular Identity
Tenofovir Disoproxil Fumarate
[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate;(E)-but-2-enedioic acid
PubChem CID: 6398764
Tenofovir disoproxil fumarate is a fumarate salt prepared from equimolar amounts of tenofovir disoproxil and fumaric acid. It is used in combination therapy for the treatment of HIV infection. It has a role as an antiviral drug, a prodrug and a HIV-1 reverse transcriptase inhibitor. It contains a tenofovir disoproxil.
2D Structure
Properties
C23H34N5O14P
Molecular Formula
635.50
Molecular Weight
g/mol
635.1840
Exact Mass
Da
260
TPSA
May have limited oral absorption
3
H-Bond Donors
18
H-Bond Acceptors
817
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Tenofovir Disoproxil Fumarate202138-50-9VireadTenofovir DFPMPA prodrugVireaPMPA-PRODRUGGS-4331-05GSK548470GSK-548470OTT9J7900IDTXSID5050426Tenofoviri disoproxili fumaras9-((R)-2-((bis(((isopropoxycarbonyl)oxy)methoxy)phosphinyl)methoxy)propyl)adenine fumarateCHEBI:63718
Data from PubChem (NCBI)
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Trials and conditions connected to Tenofovir Disoproxil Fumarate
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