Molecular Identity
tolbutamide
1-butyl-3-(4-methylphenyl)sulfonylurea
PubChem CID: 5505
Tolbutamide is an N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position. It has a role as a hypoglycemic agent, a potassium channel blocker, a human metabolite and an insulin secretagogue.
2D Structure
Properties
C12H18N2O3S
Molecular Formula
270.35
Molecular Weight
g/mol
270.1038
Exact Mass
Da
2.3
XLogP
Drug-like (Lipinski: < 5)
83.7
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
3
H-Bond Acceptors
354
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
tolbutamide64-77-7DiabetamidArkozalButamideWillbutamideArtosinIpogliconeRastinon1-Butyl-3-(p-tolylsulfonyl)urea1-Butyl-3-tosylureaDiabetolDiabutonGlycononTolbutamid
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to tolbutamide
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