Molecular Identity
2',3',5'-tri-O-acetyluridine
[(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate
PubChem CID: 20058
Uridine triacetate is an acetate ester that is uracil in which the three hydroxy hydrogens are replaced by acetate group. A prodrug for uridine, it is used for the treatment of hereditary orotic aciduria and for management of fluorouracil toxicity. It has a role as a prodrug, a neuroprotective agent and an orphan drug. It is a member of uridines and an acetate ester.
2D Structure
Properties
C15H18N2O9
Molecular Formula
370.31
Molecular Weight
g/mol
370.1012
Exact Mass
Da
-0.5
XLogP
Drug-like (Lipinski: < 5)
138
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
9
H-Bond Acceptors
660
Complexity
SMILES
Canonical SMILES
SMILES: CC(=O)OCC1C(C(C(O1)N2C=CC(=O)NC2=O)OC(=O)C)OC(=O)CIsomeric SMILES
SMILES: CC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=CC(=O)NC2=O)OC(=O)C)OC(=O)CSynonyms(20)
Uridine triacetate4105-38-82',3',5'-Tri-O-acetyluridineTriacetyluridineVistonuridine2',3',5'-TriacetyluridinePN401Tri-O-acetyluridineVistogardPN-401RG2133Triacetate d'uridineRG 2133Triacetato de uridinaCHEBI:90914
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to 2',3',5'-tri-O-acetyluridine
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