Molecular Identity
Troglitazone
5-[[4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromen-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
PubChem CID: 5591
Troglitazone is a member of chromanes and a thiazolidinone. It has a role as a ferroptosis inhibitor, an antioxidant, a hypoglycemic agent, an antineoplastic agent, a vasodilator agent, an anticonvulsant, an anticoagulant, a platelet aggregation inhibitor and an EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor.
2D Structure
Properties
C24H27NO5S
Molecular Formula
441.50
Molecular Weight
g/mol
441.1610
Exact Mass
Da
5.1
XLogP
Above Lipinski threshold
110
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
6
H-Bond Acceptors
681
Complexity
SMILES
Canonical SMILES
SMILES: CC1=C(C2=C(CCC(O2)(C)COC3=CC=C(C=C3)CC4C(=O)NC(=O)S4)C(=C1O)C)CIsomeric SMILES
SMILES: CC1=C(C2=C(CCC(O2)(C)COC3=CC=C(C=C3)CC4C(=O)NC(=O)S4)C(=C1O)C)CSynonyms(20)
troglitazone97322-87-7RezulinRomglizonePrelayCS-045RomozinNoscaltroglitazonatroglitazonumCI-991DTXSID8023719GR92132XGR-92132X5-(4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2,4-dione
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Troglitazone
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