Molecular Identity
Uracil
1H-pyrimidine-2,4-dione
PubChem CID: 1174
Uracil is a common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription. It has a role as a prodrug, an allergen, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and a Daphnia magna metabolite. It is a pyrimidine nucleobase and a pyrimidone. It is a tautomer of a (4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one.
2D Structure
Properties
C4H4N2O2
Molecular Formula
112.09
Molecular Weight
g/mol
112.0273
Exact Mass
Da
-1.1
XLogP
Drug-like (Lipinski: < 5)
58.2
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
2
H-Bond Acceptors
161
Complexity
SMILES
Canonical SMILES
SMILES: C1=CNC(=O)NC1=OIsomeric SMILES
SMILES: C1=CNC(=O)NC1=OSynonyms(20)
uracil66-22-8pyrimidine-2,4(1H,3H)-dione2,4(1H,3H)-PyrimidinedionePyrodPirodHybar X2,4-Dioxopyrimidine2,4-Pyrimidinedione1H-Pyrimidine-2,4-dione1,2,3,4-tetrahydropyrimidine-2,4-dioneDTXSID402142456HH86ZVCTNSC-3970SQ-6201
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Uracil
Loading drug network...