Valganciclovir
[2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]-3-hydroxypropyl] (2S)-2-amino-3-methylbutanoate
Molecular Identity
Valganciclovir
[2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]-3-hydroxypropyl] (2S)-2-amino-3-methylbutanoate
PubChem CID: 135413535
Valganciclovir is the L-valinyl ester of ganciclovir, into which it is rapidly converted by intestinal and hepatic esterases. It is a synthetic analogue of 2'-deoxyguanosine. It has a role as an antiviral drug and a prodrug. It is a member of purines and a L-valyl ester. It is functionally related to a guanine and a ganciclovir.
2D Structure
Properties
C14H22N6O5
Molecular Formula
354.36
Molecular Weight
g/mol
354.1652
Exact Mass
Da
-1.5
XLogP
Drug-like (Lipinski: < 5)
167
TPSA
May have limited oral absorption
4
H-Bond Donors
8
H-Bond Acceptors
528
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Valganciclovir175865-60-8GCU97FKN3RL-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)-3-hydroxypropyl esterDTXSID8048288CHEBI:63635L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]-3-hydroxypropyl (2S)-2-amino-3-methylbutanoatevalganciclovirum2-((2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy)-3-hydroxypropyl (2S)-2-amino-3-methylbutanoateRefChem:56199ganciclovir L-valyl esterGlyTouCan:G39772PVGanciclovir L valyl EsterDTXCID3028263
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Valganciclovir
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