Molecular Identity
Yohimbine
methyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
PubChem CID: 8969
Yohimbine is an indole alkaloid with alpha2-adrenoceptor antagonist activity. It is produced by Corynanthe johimbe and Rauwolfia serpentina. It has a role as a dopamine receptor D2 antagonist, an alpha-adrenergic antagonist and a serotonergic antagonist. It is functionally related to a yohimbic acid.
2D Structure
Properties
C21H26N2O3
Molecular Formula
354.40
Molecular Weight
g/mol
354.1943
Exact Mass
Da
2.9
XLogP
Drug-like (Lipinski: < 5)
65.6
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
4
H-Bond Acceptors
555
Complexity
SMILES
Canonical SMILES
SMILES: COC(=O)C1C(CCC2C1CC3C4=C(CCN3C2)C5=CC=CC=C5N4)OIsomeric SMILES
SMILES: COC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)OSynonyms(20)
Yohimbine146-48-5YohimbinQuebrachineCorynineQuebrachinAPHRODINEYohimbic acid methyl ester(+)-YohimbineYohimbinumDTXSID904013017alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester2Y49VWD90Qmethyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Yohimbine
Loading drug network...