Zamzetoclax
N-[(3'R,4S,6'R,7'S,8'Z,11'S)-7-chloro-7'-methoxy-11'-methyl-13',15'-dioxospiro[2,3-dihydro-1H-naphthalene-4,22'-20-oxa-13lambda6-thia-1,14-diazatetracyclo[14.7.2.03,6.019,24]pentacosa-8,13,16(25),17,19(24)-pentaene]-13'-yl]-3-methoxy-1-methylpyrazole-4-carboxamide
Molecular Identity
Zamzetoclax
N-[(3'R,4S,6'R,7'S,8'Z,11'S)-7-chloro-7'-methoxy-11'-methyl-13',15'-dioxospiro[2,3-dihydro-1H-naphthalene-4,22'-20-oxa-13lambda6-thia-1,14-diazatetracyclo[14.7.2.03,6.019,24]pentacosa-8,13,16(25),17,19(24)-pentaene]-13'-yl]-3-methoxy-1-methylpyrazole-4-carboxamide
PubChem CID: 146261163
2D Structure
Properties
C38H46ClN5O6S
Molecular Formula
736.30
Molecular Weight
g/mol
735.2857
Exact Mass
Da
7.2
XLogP
Above Lipinski threshold
133
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
8
H-Bond Acceptors
1430
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(16)
ZamzetoclaxMcl-1 inhibitor 82388471-31-4Mcl-1-inhibitor-8CHEMBL5839076SCHEMBL21576401BDBM4496152388470-64-0EX-A10028US10703733, Example 228DA-65295HY-145826HY-163681CS-0434111CS-1099157
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Zamzetoclax
Loading drug network...