Effects of Dynorphin 1-13 on Heroin Addiction - 1

University of Minnesota

Overview

The purpose of this study is to evaluate the effects of IV dynorphin in humans during acute heroin abstinence, in order to determine that dynorphin suppresses acute opiate withdrawal, reduces opiate craving, and is safe at doses required to produce the above effects.

Randomized double blinded study of the effects of a single IV dose of dynorphin A 1-13 on heroin withdrawal in human opiate addicts

Study Type

INTERVENTIONAL

Purpose

TREATMENT

Masking

DOUBLE

Conditions

Interventions

Dynorphin 1 - 13DRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: opiate addict between the ages of 18-55 Exclusion Criteria: Regular abuse of other drugs, unstable medical conditions

Locations (1)

U of Minnesota School of Medicine

Minneapolis, Minnesota, United States

Outcomes

Primary Outcomes

Craving scale

Data from ClinicalTrials.gov

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