Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2

University of Chicago12 enrolled

Overview

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To evaluate: cold water immersion modulates the reinforcing effects of nitrous oxide in healthy volunteers.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Interventions

0% N2ODRUG

Subjects will inhale 100% oxygen with no N2O for 25 min then immerse forearm in warm water and cold water

40% N2ODRUG

Subjects will inhale 40% N2O then immerse forearm in warm water and cold water

Eligibility

Sex: ALLMin age: 21 YearsMax age: 32 YearsHealthy volunteers:

Medical Language ↔ Plain English

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Locations (1)

University of Chicago, Anesthesia & Critical Care

Chicago, Illinois, United States

Outcomes

Primary Outcomes

Subject's choice of intervention

Time frame: After sampling trials

Data from ClinicalTrials.gov

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