The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To evaluate the acute and residual effects of subanesthetic concentrations of isoflurane/nitrous oxide combinations in healthy volunteers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
10
University of Chicago, Anesthesia & Critical Care
Chicago, Illinois, United States
Logical reasoning test
Time frame: 15 & 30 min inhalation and 5, 30, & 60 min post inhalation
Free recall memory test
Time frame: 15 & 30 min inhalation and 5, 30, & 60 min post inhalation
Auditory reaction time
Time frame: 15 & 30 min inhalation and 5,30 & 60 min post inhalation
Digit symbol substitution test
Time frame: 2,15 & 30 min inhalation and 5,30 & 60 min post inhalation
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