Tryptophan and Behavior Therapy for Cocaine Abuse - 1

National Institute on Drug Abuse (NIDA)200 enrolled

Overview

The purpose of this study is to assess the efficacy of tryptophan vs. placebo, and voucher payments vs. a control condition, in the treatment of cocaine dependence.

This clinical trial uses a 2 by 2 design to compare tryptophan to placebo, and voucher incentives vs. a control condition, in the outpatient treatment of cocaine dependence- using a relapse prevention model of treatment intervention.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

200

Conditions

Cocaine-Related Disorders

Interventions

TryptophanDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Cocaine dependent Exclusion Criteria: * Physically dependent on drugs of abuse other than cocaine * Significant medical or psychiatric illness (besides substance abuse disorder) * Pregnant

Locations (1)

Johns Hopkins University School of Medicine

Baltimore, Maryland, United States

Outcomes

Primary Outcomes

Side effects

Retention

Cocaine use

Cocaine craving

Other drug use

Psychosocial functioning

Data from ClinicalTrials.gov

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