Evaluation of Liquid vs. Tablet Buprenorphine - 6

National Institute on Drug Abuse (NIDA)1 enrolled

Overview

The purpose of this study is to evaluate the steady-state pharmacokinetics and bioavailability of buprenorphine sublingual tablets vs. sublingual solution.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Opioid-Related Disorders

Interventions

BuprenorphineDRUG

Eligibility

Sex: ALLMin age: 21 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: M/F ages 21-50. Meet DSM-IV criteria for opioid dependence. Agree to conditions of the study and sign informed consent. Exclusion Criteria: Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nuring women. Dependence on ETOH or benzodiazepines or other sedative/hypnotics. Acute hepatitis. Other medical condtions that deem participation to be unsafe.

Locations (1)

Friends Research Institute

Los Angeles, California, United States

Outcomes

Primary Outcomes

Subjective and observer rater physiological effects of bup

Data from ClinicalTrials.gov

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